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The grip of the pantyhose, the stranglehold of the scarf, and the bite of the tight shoes made Rachel want the interview to end, she longed for a cotton T-shirt and jeans.
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The grip of the pantyhose, the stranglehold of the scarf, and the bite of the tight shoes made Rachel want the interview to end. She longed for a cotton T-shirt and jeans.

The grip of the pantyhose, the stranglehold of the scarf, and the bite of the tight shoes made Rachel want the interview to end is a main clause. She longed for a cotton T-shirt and jeans is the second main clause.

You are always correct when you use a period between the two main clauses that create the comma splice.

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