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Bored with the lecture on comma splices and fused sentences, Jayson started poking Kim with the sharp tip of his pencil finally she whirled around, threatening to slug him if he interrupted her learning one more time.
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Bored with the lecture on comma splices and fused sentences, Jayson started poking Kim with the sharp tip of his pencil; finally, she whirled around, threatening to slug him if he interrupted her learning one more time.

Jayson started poking Kim with the sharp tip of his pencil is a main clause. She whirled around ... is a second main clause.

A semicolon is an excellent way to join two main clauses that are closely related in meaning.

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