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During the summer when a variety of fruit is in season, Melville always avoids the fresh peaches, the fuzzy skin brushing against his lips makes Melville think that he is eating a small rodent.

You need no correction between think and that. The fuzzy skin brushing against his lips makes Melville think is a main clause. That he is eating a small rodent is a subordinate clause. You must connect a subordinate clause to a main clause.

When the subordinate clause follows the main clause, as in the example above, you generally need no punctuation.

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