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If Chris hopes to survive in his 8 a.m. English class, he needs to discover caffeine even when he has a test, his head hits the desk by 8:05, and snores soon escape his mouth.

The comma between 8:05 and and is completely correct. His head hits the desk by 8:05 is a main clause. Snores soon escape his mouth is another main clause.

A comma and a coordinating conjunction like and can legally connect two main clauses.

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